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The 5th Annual Meeting for Whole-Organism Science Society and The 14th Annual Meeting of Whole-Cell Project of Thermus thermophilus HB8

Recent articles of T. thermophilus

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Protein expression vectors are now available from BRC

　1,685 Clones of Thermus thermophilus HB8 are available from RIKEN DNA bank.

http://dna.brc.riken.jp/en/thermus_en.html

　　All clones are constructed in pET expression system without tag residues.
　　Clone set: Clones are shipped as frozen recombinant E. coli DH5a in 96-well plates with dry-ice.
　　Single clone: Clone(s) is shipped as DNA solution in TE buffer in individual tube.

TTHB8 Genomic DNA is available for purchase at TaKaRa.

Product Name

TaKaRa Code

Thermus thermophilus HB8 Genomic DNA Solution

3071

【What's The Structural-Biological Whole Cell Project?】

　"Structural-Biological Whole Cell Project" aims to understand all biological phenomena in the cell of an extremely thermophilic bacterium, Thermus thermophilus HB8 based on structural information of biomolecule. Owing to the advantage for structural analysis, the coming functional genomics, and moreover collaboration with groups of bioinformatics and detailed functional analysis, T. thermophilus HB8 is expected to be an excellent model organism for atomic biology, which will be a new research field in 21th century.

【What's The Extremely Thermophilic Bacterium?】

T. thermophilus HB8： It can grow to 85 ℃.	Gene is the blueprint for protein which functions by taking a highly ordered structure.


	human genes	about 22,000
	T. thermophilus HB8 genes	about 2,200

	About 1,000 fundamental genes are the minimum requirement for a life.

	They exist in common in all living things, also including a man. They also exist in T. thermophilus HB8!
・ It can grow at the highest temperature in all organisms with the gene manipulating system. ・ Protein from this bacterium is highly stable and easy to crystallize.
Findspot of Thermus thermophilus HB8

Electron micrograph of Thermus thermophilus HB8

Let the thermophilic bacterium, T. thermophilus HB8, be a model organism. We aim to elucidate all highly ordered structures of proteins encoded in this genome and analyze functions through their structures.

It is hoped that the biological phenomena of one organism whole is understood on the level of physical science based on the 3D structure of molecule.

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